Hispidin

Hispidin is a natural substance. It can also be synthetised. Hispidin 4-O-β-d-glucopyranoside can be found in Pteris ensiformis whereas hispidin derivatives, such as phellibaumins, can be found in the edible mushroom Inonotus xeranticus or Phellinus. Hispidin is a precursor of fungal luciferin, a compound responsible for light emission by luminous mushrooms.

Product information

CAS Number: 555-55-5

Molecular Weight: 246.22

Formula: C13H10O5

Chemical Name: 6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone

Smiles: OC1C=C(C=CC2=CC(O)=C(O)C=C2)OC(=O)C=1

InChiKey: SGJNQVTUYXCBKH-HNQUOIGGSA-N

InChi: InChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Smolskaite L, Slapšyte G, Mierauskiene J, Dedonyte V, Venskutonis PR. Antioxidant and Genotoxic Properties of Hispidin Isolated from the Velvet-Top Mushroom, Phaeolus schweinitzii (Agaricomycetes). Int J Med Mushrooms. 2017;19(11):967-980. doi: 10.1615/IntJMedMushrooms.2017024522. PubMed PMID: 29345559.
2. Song TY, Yang NC, Chen CL, Thi TLV. Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells. Oxid Med Cell Longev. 2017;2017:4824371. doi: 10.1155/2017/4824371. Epub 2017 Oct 17. PubMed PMID: 29181125; PubMed Central PMCID: PMC5664345.
3. Tian LW, Feng Y, Tran TD, Shimizu Y, Pfeifer T, Vu HT, Quinn RJ. Achyrodimer F, a tyrosyl-DNA phosphodiesterase I inhibitor from an Australian fungus of the family Cortinariaceae. Bioorg Med Chem Lett. 2017 Sep 1;27(17):4007-4010. doi: 10.1016/j.bmcl.2017.07.062. Epub 2017 Jul 24. PubMed PMID: 28797798.

Products are for research use only. Not for human use.