Description
m-PEG12-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2413368-61-1
Molecular Weight: 576.74
Formula: C25H52O12S
Chemical Name: 2,5,8,11,14,17,20,23,26,29,32,35-dodecaoxaheptatriacontane-37-thiol
Smiles: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCS
InChiKey: MXDXXEVQFMVAIA-UHFFFAOYSA-N
InChi: InChI=1S/C25H52O12S/c1-26-2-3-27-4-5-28-6-7-29-8-9-30-10-11-31-12-13-32-14-15-33-16-17-34-18-19-35-20-21-36-22-23-37-24-25-38/h38H,2-25H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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