BDP FL-PEG4-TCO

BDP FL-PEG4-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2183473-16-5

Molecular Weight: 662.57

Formula: C33H49BF2N4O7

Chemical Name: 4-{2-[(14-{[(cyclooct-4-en-1-yloxy)carbonyl]amino}-3,6,9,12-tetraoxatetradecan-1-yl)carbamoyl]ethyl}-2,2-difluoro-10,12-dimethyl-1λ⁵,3-diaza-2-boratricyclo[7.3.0.0³,⁷]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide

Smiles: CC1C=C(C)C2=CC3=CC=C(CCC(=O)NCCOCCOCCOCCOCCNC(=O)OC4CCCC=CCC4)N3[B-](F)(F)[N+]=12 |t:38|

InChiKey: FISJDIFFUFNJNS-ARJAWSKDSA-N

InChi: InChI=1S/C33H49BF2N4O7/c1-26-24-27(2)39-31(26)25-29-11-10-28(40(29)34(39,35)36)12-13-32(41)37-14-16-43-18-20-45-22-23-46-21-19-44-17-15-38-33(42)47-30-8-6-4-3-5-7-9-30/h3-4,10-11,24-25,30H,5-9,12-23H2,1-2H3,(H,37,41)(H,38,42)/b4-3-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.