Description
Bromo-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 220568-33-2
Molecular Weight: 297.19
Formula: C11H21BrO4
Chemical Name: 2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}oxane
Smiles: BrCCOCCOCCOC1CCCCO1
InChiKey: NMSUTJVEBXQTQM-UHFFFAOYSA-N
InChi: InChI=1S/C11H21BrO4/c12-4-6-13-7-8-14-9-10-16-11-3-1-2-5-15-11/h11H,1-10H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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