K-Ras G12C-IN-1


Catalog No. Size PriceQuantity
M11215-2 Solid 2 mg $170
M11215-10 Solid 10 mg $560

Description

K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.IC50 value:Target: K-ras G12C inhibitor

Product information

CAS Number: 1629265-17-3

Molecular Weight: 448.34

Formula: C22H23Cl2N3O3

Chemical Name: 1-{4-[2-({2',6-dichloro-4-methoxy-[1,1'-biphenyl]-3-yl}amino)acetyl]piperazin-1-yl}prop-2-en-1-one

Smiles: COC1=CC(Cl)=C(C=C1NCC(=O)N1CCN(CC1)C(=O)C=C)C1=CC=CC=C1Cl

InChiKey: ZJWLFLPGQCYBSE-UHFFFAOYSA-N

InChi: InChI=1S/C22H23Cl2N3O3/c1-3-21(28)26-8-10-27(11-9-26)22(29)14-25-19-12-16(18(24)13-20(19)30-2)15-6-4-5-7-17(15)23/h3-7,12-13,25H,1,8-11,14H2,2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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