Catalog No. Size PriceQuantity
M12084-2 2mg solid $170
M12084-10 10mg solid $540


IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK). IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.

Product information

CAS Number: 1221412-23-2

Molecular Weight: 485.45

Formula: C22H23N5O8

Chemical Name: [(2R, 3R, 4R, 5R)-3, 4-bis(acetyloxy)-5-{6-[(3-hydroxyphenyl)amino]-9H-purin-9-yl}oxolan-2-yl]methyl acetate

Smiles: CC(=O)OC[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H]1OC(C)=O)N1C=NC2C1=NC=NC=2NC1=CC(O)=CC=C1


InChi: InChI=1S/C22H23N5O8/c1-11(28)32-8-16-18(33-12(2)29)19(34-13(3)30)22(35-16)27-10-25-17-20(23-9-24-21(17)27)26-14-5-4-6-15(31)7-14/h4-7,9-10,16,18-19,22,31H,8H2,1-3H3,(H,23,24,26)/t16-,18-,19-,22-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C) DMSO: 97 mg/mL(199.81 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. LinZhang Huang, et al. J Lipid Res. 2015 May;56(5):986-97.
  2. Jinjin Yu, et al. Toxicol Appl Pharmacol. 2019 Oct 15;381:114732.
  3. Weipeng Ge, et al. Eur J Pharmacol. 2019 Aug 15;857:172442.

Products are for research use only. Not for human use.

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