Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system.
CAS Number: 674-38-4
Molecular Weight: 161.22
Chemical Name: 1-(trimethylazaniumyl)propan-2-yl carbamate
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
Bethanechol (0.3-300 μM) significantly reduces ileal pacemaker potentials.
Bethanechol (2-12 mg/kg; i.p.) induces drinking and increased urine output of rats in a dose-dependent fashion.
- Inderbir S. Padda, et al. Bethanechol. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.
- Julia Yuen Hang Liu, et al. Acetylcholine exerts inhibitory and excitatory actions on mouse ileal pacemaker activity: role of muscarinic versus nicotinic receptors. Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319(1):G97-G107.
- M J Fregly, et al. Bethanechol-induced water intake in rats: possible mechanisms of induction. Pharmacol Biochem Behav. 1982 Oct;17(4):727-32.
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