MK-6913

MK-6913 (Tetrahydrofluoroene 52) is a potent and selective estrogen receptor β agonist.

Product information

CAS Number: 1398510-92-3

Molecular Weight: 401.50

Formula: C25H27N3O2

Synonym:

Tetrahydrofluoroene 52

Chemical Name: (9aS)-3-tert-butyl-9a-(2-phenoxyethyl)-3H,7H,8H,9H,9aH,10H-fluoreno[1,2-d][1,2,3]triazol-7-one

Smiles: CC(C)(C)N1N=NC2C1=CC=C1C3=CC(=O)CC[C@]3(CC=21)CCOC1C=CC=CC=1

InChiKey: LYLIIGQPIKTONH-RUZDIDTESA-N

InChi: InChI=1S/C25H27N3O2/c1-24(2,3)28-22-10-9-19-20(23(22)26-27-28)16-25(12-11-17(29)15-21(19)25)13-14-30-18-7-5-4-6-8-18/h4-10,15H,11-14,16H2,1-3H3/t25-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MK-6913 (Tetrahydrofluoroene 52), a highly substituted tetrahydrofluorene derivative, is a potent and selective estrogen receptor β agonist.

References:

1. Matthew L. Maddess, et al. Enantioselective Synthesis of a Highly Substituted Tetrahydrofluorene Derivative as a Potent and Selective Estrogen Receptor Beta Agonist. Org Process Res Dev. 2014 Mar 3;18(4): 528–538.

Products are for research use only. Not for human use.