Sepimostat dimethanesulfonate

Catalog No. Size PriceQuantity
M23618-C Contact for quotation $100Unavailable


Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7 µM.

Product information

CAS Number: 103926-82-5

Molecular Weight: 469.51

Formula: C22H23N5O5S

Chemical Name: 6-carbamimidoylnaphthalen-2-yl 4-[(4,5-dihydro-1H-imidazol-2-yl)amino]benzoate; methanesulfonic acid

Smiles: CS(O)(=O)=O.NC(=N)C1=CC2=CC=C(C=C2C=C1)OC(=O)C1C=CC(=CC=1)NC1NCCN=1


InChi: InChI=1S/C21H19N5O2.CH4O3S/c22-19(23)16-2-1-15-12-18(8-5-14(15)11-16)28-20(27)13-3-6-17(7-4-13)26-21-24-9-10-25-21;1-5(2,3)4/h1-8,11-12H,9-10H2,(H3,22,23)(H2,24,25,26);1H3,(H,2,3,4)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect.

Products are for research use only. Not for human use.

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