Catalog No. size PriceQuantity
M6598-2 2mg solid $117
M6598-10 10mg solid $470


PD-151746 is an inhibitor of calpains 1 and 2.

Product information

CAS Number: 179461-52-0

Molecular Weight: 237.25

Formula: C11H8FNO2S



PD 151746


Chemical Name:    3-(5-Fluoro-3-indolyl)-2-mercapto-2-propenoic Acid

Smiles: OC(=O)C(S)=CC1=CNC2=CC=C(F)C=C12


InChi: InChI=1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200


  1. Lei H, Li X, Jing B, Xu H, Wu Y. Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in Psoriasis. PLoS One. 2017 Jan 6;12(1):e0169788. doi: 10.1371/journal.pone.0169788. eCollection 2017. PubMed PMID: 28060905; PubMed Central PMCID: PMC5218466.
  2. Meier M, Klein HH, Kramer J, Drenckhan M, Schutt M. Calpain inhibition impairs glycogen syntheses in HepG2 hepatoma cells without altering insulin signaling. J Endocrinol. 2007 Apr;193(1):45-51. PubMed PMID: 17400802.
  3. Jost MM, Jost P, Klein J, Klein HH. The beta3-adrenergic agonist CL316,243 inhibits insulin signaling but not glucose uptake in primary human adipocytes. Exp Clin Endocrinol Diabetes. 2005 Sep;113(8):418-22. PubMed PMID: 16151974.

Products are for research use only. Not for human use.

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