Cambendazol

Cambendazole is one of the most effective agents for the therapy of human strongyloidiasis.

Product information

CAS Number: 26097-80-3

Molecular Weight: 302.35

Formula: C14H14N4O2S

Synonym:

Novazole

Noviben

Equiben

Cambendazole

Chemical Name: isopropyl (2-(thiazol-4-yl)-1H-benzo[d]imidazol-5-yl)carbamate

Smiles: CC(C)OC(=O)NC1C=C2N=C(NC2=CC=1)C1=CSC=N1

InChiKey: QZWHWHNCPFEXLL-UHFFFAOYSA-N

InChi: InChI=1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Andrade SR, Scarminio IS, Nery MM, de Oliveira AC. Comparison of multivariate calibration methods to determine simultaneously mebendazole-cambendazole and mebendazole-thiabendazole in pharmaceutical preparations by UV-visible spectrophotometry. J Pharm Biomed Anal. 2003 Nov 24;33(4):655-65. PubMed PMID: 14623591.
2. Lyons ET, Drudge JH, Tolliver SC, Swerczek TW, Stamper S, Granstrom DE. Control of cambendazole-resistant small strongyles (Population S) with oxibendazole in a pony band: an 8 year field test (1984-1992). Vet Parasitol. 1994 Apr;52(3-4):271-7. PubMed PMID: 8073610.
3. Sharma RK, Singh K, Saxena KK. Effect of cambendazole and haloxon on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae (Nematoda). Angew Parasitol. 1990 May;31(2):101-5. PubMed PMID: 2389827.
4. Grove DI, Northern C. The effects of thiabendazole, mebendazole and cambendazole in normal and immunosuppressed dogs infected with a human strain of Strongyloides stercoralis. Trans R Soc Trop Med Hyg. 1988;82(1):146-9. PubMed PMID: 3176142.

Products are for research use only. Not for human use.