Catalog No. size PriceQuantity
M7085-2 2mg solid $150
M7085-10 10mg solid $603


OUN87710, also known as MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor.

Product information

CAS Number: 502887-71-0

Molecular Weight: 369.39

Formula: C16H17F2N3O3S







OUN 87710

Chemical Name: N-(4-(difluoromethoxy)phenyl)-2-((6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)thio)acetamide

Smiles: CCCC1=CC(=O)NC(=N1)SCC(=O)NC1=CC=C(C=C1)OC(F)F


InChi: InChI=1S/C16H17F2N3O3S/c1-2-3-11-8-13(22)21-16(20-11)25-9-14(23)19-10-4-6-12(7-5-10)24-15(17)18/h4-8,15H,2-3,9H2,1H3,(H,19,23)(H,20,21,22)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

MMP-9-IN-1 (compound 2; 100 μM; 14 hours) does not cause notable cytotoxicity. MMP-9-IN-1 (compound 2; 10 μM) significantly inhibits cell proliferation of HT-1080 and MDA-MB-435 cells.

In Vivo:

MMP-9-IN-1 (compound 2; 20 mg/kg; intraperitoneal and intratumoral injection alternately; 6 days/week; for 14 weeks) results in a profound delay in tumor growth in NCR-Nu mice bearing MDA-MB-435/GFP tumor. MMP-9-IN-1 inhibits cancer cell metastasis in vivo.


  1. Dufour A, et al. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res. 2011 Jul 15;71(14):4977-88.

Products are for research use only. Not for human use.

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