Catalog No. size PriceQuantity
M7085-2 2mg solid $150
M7085-10 10mg solid $603



Product Information

OUN87710, also known as MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor. OUN87710 was first reported by Antoine Dufour et al (Cancer Res. 2011, 71(14): 4977–4988, compound 2). OUN87710 has CAS#502887-71-0, no formal name For the convenience of scientific communication, we named it as OUN87710combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature.


Chemical Formula: C16H17F2N3O3S


Exact Mass: 369.0959

Molecular Weight: 369.3868


Elemental Analysis: C, 52.03; H, 4.64; F, 10.29; N, 11.38; O, 12.99; S, 8.68









OUN 87710


Chemical Name: N-(4-(difluoromethoxy)phenyl)-2-((6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)thio)acetamide


InChi Key: 



InChi Code: InChI=1S/C16H17F2N3O3S/c1-2-3-11-8-13(22)21-16(20-11)25-9-14(23)19-10-4-6-12(7-5-10)24-15(17)18/h4-8,15H,2-3,9H2,1H3,(H,19,23)(H,20,21,22)


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


In Vitro:

MMP-9-IN-1 (compound 2; 100 μM; 14 hours) does not cause notable cytotoxicity.

MMP-9-IN-1 (compound 2; 10 μM) significantly inhibits cell proliferation of HT-1080 and MDA-MB-435 cells.


In Vivo:

MMP-9-IN-1 (compound 2; 20 mg/kg; intraperitoneal and intratumoral injection alternately; 6 days/week; for 14 weeks) results in a profound delay in tumor growth in NCR-Nu mice bearing MDA-MB-435/GFP tumor.

MMP-9-IN-1 inhibits cancer cell metastasis in vivo.





  1. Dufour A, et al. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res. 2011 Jul 15;71(14):4977-88.


Products are for research use only. Not for human use.

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