LM22A-4


Catalog No. Size PriceQuantity
M7440-2 2mg solid $90
M7440-10 10mg solid $270
M7440-100 100mg solid $1,620

Description

LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.

Product information

CAS Number: 37988-18-4

Molecular Weight: 339.34

Formula: C15H21N3O6

Chemical Name: N1,N3,N5-tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide

Smiles: OCCNC(=O)C1C=C(C=C(C=1)C(=O)NCCO)C(=O)NCCO

InChiKey: RGWJKANXFYJKHN-UHFFFAOYSA-N

InChi: InChI=1S/C15H21N3O6/c19-4-1-16-13(22)10-7-11(14(23)17-2-5-20)9-12(8-10)15(24)18-3-6-21/h7-9,19-21H,1-6H2,(H,16,22)(H,17,23)(H,18,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 68 mg/mL (200.39 mM) Water 68 mg/mL (200.39 mM) Ethanol 3 mg/mL (8.84 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Yu G, et al. Protective effects of LM22A-4 on injured spinal cord nerves. Int J Clin Exp Pathol. 2015 Jun 1;8(6):6526-32. eCollection 2015.
  2. Kajiya M, et al. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. Int Immunopharmacol. 2014 Apr;19(2):245-52.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed