Chlorogenic acid


Catalog No. Size PriceQuantity
M7644-2 2mg solid $80
M7644-10 10mg solid $240

Description

Chlorogenic acid (CGA) is a natural chemical compound which is the ester of caffeic acid and (-)-quinic acid. It is an important biosynthetic intermediate in lignin biosynthesis. This compound, known as an antioxidant, may also slow the release of glucose into the bloodstream after a meal. The term chlorogenic acids can also refer to a related family of esters of hydroxycinnamic acids (caffeic acid, ferulic acid and p-coumaric acid) with quinic acid. Chlorogenic acids contain no chlorine.

Product information

CAS Number: 327-97-9

Molecular Weight: 354.31

Formula: C16H18O9

Synonym:

3(34Dihydroxycinnamoyl)quinate

3(34Dihydroxycinnamoyl)quinic acid

3Caffeoylquinate

3Caffeoylquinic acid

3CQA

3OCaffeoylquinic acid

Chlorogenate

Heriguard

3transCaffeoylquinic acid

Chemical Name: (1S, 3R, 4R, 5R)-3-{[(2Z)-3-(3, 4-dihydroxyphenyl)prop-2-enoyl]oxy}-1, 4, 5-trihydroxycyclohexane-1-carboxylic acid

Smiles: OC(=O)[C@]1(O)C[C@@H](O)[C@@H](O)[C@@H](C1)OC(=O)/C=C\C1=CC(O)=C(O)C=C1

InChiKey: CWVRJTMFETXNAD-XYXZIBEBSA-N

InChi: InChI=1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2-/t11-,12-,14-,16+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 71 mg/mL(200.38 mM). Water: 18 mg/mL(50.8 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Park JJ, et al. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway. Cell Oncol (Dordr). 2015 Jan 6.
  2. Park SH, et al. IRAK4 as a Molecular Target in the Amelioration of Innate Immunity-Related Endotoxic Shock and Acute Liver Injury by Chlorogenic Acid. J Immunol. 2015 Feb 1;194(3):1122-30.
  3. Kang JW, et al. Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats. Biomol Ther (Seoul). 2014 Sep;22(5):420-5.

Products are for research use only. Not for human use.

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