Glycyrrhizic acid


Catalog No. Size PriceQuantity
M7739-2 2mg solid $80
M7739-10 10mg solid $240

Description

Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.

Product information

CAS Number: 1405-86-3

Molecular Weight: 822.93

Formula: C42H62O16

Synonym:

Glycyrrhizin

Glizigen

Liquorice

Chemical Name: (2S, 3S, 4S, 5R, 6S)-6-{[(3S, 4aR, 6aR, 6bS, 8aS, 11S, 12aR, 14aR, 14bS)-11-carboxy-4, 4, 6a, 6b, 8a, 11, 14b-heptamethyl-14-oxo-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicen-3-yl]oxy}-5-{[(2R, 3R, 4S, 5S, 6S)-6-carboxy-3, 4, 5-trihydroxyoxan-2-yl]oxy}-3, 4-dihydroxyoxane-2-carboxylic acid

Smiles: CC1(C)[C@@H]2CC[C@]3(C)[C@H](C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O)[C@@]2(C)CC[C@@H]1O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O

InChiKey: LPLVUJXQOOQHMX-QWBHMCJMSA-N

InChi: InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 100 mg/mL(121.51 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. D Dhingra, et al. Indian J Pharmacol. 2005, 37:390-4.
  2. Gong G, et al. PLoS One. 2014, 9(3):e89450.
  3. Tanahashi T, et al. J Steroid Biochem Mol Biol, 2002,80(4-5):441-7.

Products are for research use only. Not for human use.

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